Organic Acids
Medchemexpress LLC MS9427 TFA | 98.4% | 1107.50 | 5 MG
MS9427 TFA is a potent PROTAC EGFR degrader that selectively targets and degrades mutant EGFR through both the ubiquitin/proteasome system (UPS) and autophagy/lysosome pathways. This compound effectively inhibits the proliferation of NSCLC cells and shows antiproliferative activity against HCC-827 cells.
- Potent PROTAC EGFR degrader
- Selectively degrades mutant EGFR
- Utilizes ubiquitin/proteoteasome system and autophagy/lysosome pathways
- Inhibits proliferation of non-small cell lung cancer (NSCLC) cells
- Exhibits antiproliferative activity against HCC-827 cells
- Induces EGFRDel19 degradation
FUJIFILM Biosciences Trifluoroacetic Acid Solution (for Gradient Elution) | 76-05-1 | MFCD00004169 | 40mL
Trifluoroacetic Acid Solution (for Gradient Elution) | Putity: 25% | MW: 114.022 | 76-05-1 | MFCD00004169 | 40mL
Medchemexpress LLC Mtvkpabc-p5 TFA | 98.8% | 1190.22 | C54H74F3N11O16 | 25 MG
MTvkPABC-P5 TFA is the trifluoroacetic acid (TFA) salt of a synthetic Toll-like receptor 7 (TLR7) agonist. It functions as an immune stimulant used in research applications, including the synthesis of immune-stimulating antibody conjugates (ISACs).
- Acts as a TLR7 agonist and immune stimulant.
- Suitable for synthesis of immune-stimulating antibody conjugates (ISACs).
- Provided as a solid TFA salt.
- High purity, 98.8%.
- Molecular weight 1190.22, formula C54H74F3N11O16.
- Available as 25 MG quantity.
Medchemexpress LLC PSMA I&S TFA | 98.15% | 1413.43 | 5 MG
PSMA I&S (TFA) is a precursor of the 99mTc-labeled PSMA-targeting ligand, intended for research use only.
- Precursor of 99mTc-labeled PSMA-targeting ligand
- For research use only
Medchemexpress LLC Cilengitide TFA | 199807-35-7 | 99.9% | 702.68 | 25 MG
Cilengitide is a potent and selective integrin inhibitor for αvβ3 and αvβ5 receptor, with IC50 values of 4 nM and 79 nM, respectively. It inhibits integrin-mediated binding to vitronectin.
- Potent and selective integrin inhibitor
- Targets αvβ3 receptor with IC50 of 4 nM
- Targets αvβ5 receptor with IC50 of 79 nM
Medchemexpress LLC Thanatin TFA | 99.7% | 2433.92 (free base) | 5 MG
Thanatin TFA is an inducible cationic antimicrobial peptide (AMP) with a single-disulfide-bond-containing β-hairpin structure. It exhibits broad-spectrum activity against Gram-negative and Gram-positive bacteria, as well as various fungal species. This peptide functions by competitively replacing divalent cations from the bacterial outer membrane, leading to its disruption.
- Exhibits broad-spectrum activity against Gram-negative and Gram-positive bacteria.
- Effective against various species of fungi.
- Disrupts bacterial outer membrane.
- Potent inhibitory effect on NDM-1-producing E. coli and K. pneumoniae strains.
- Increases survival rates and decreases bacterial titers in infected mice.
- Rescues pathological damages in a dose-dependent manner in vivo.
Medchemexpress LLC CCZ01048 TFA | 98.5% | 1622.75 | 5 MG
CCZ01048 TFA is an α-MSH analogue that exhibits high binding affinity to melanocortin 1 receptor (MC1R) with a Ki of 0.31 nM. It shows rapid internalization into B16F10 melanoma cells and demonstrates high in vivo stability, making it a promising candidate for PET imaging of malignant melanoma.
- α-MSH analogue
- High binding affinity to melanocortin 1 receptor (MC1R) with a Ki of 0.31 nM
- Rapid internalization into B16F10 melanoma cells
- High in vivo stability
- Promising candidate for PET imaging of malignant melanoma
Medchemexpress LLC BRP TFA (BRINP2-related peptide) TFA | 1540.88 (free base) | 5 MG
BRP (BRINP2-related peptide) TFA is a peptide that exhibits anti-obesity activity by activating FOS. It functions independently of leptin, GLP-1 receptor, and melanocortin 4 receptor.
- Exhibits anti-obesity activity
- Activates FOS in the central nervous system
- Functions independently of leptin, GLP-1 receptor, and melanocortin 4 receptor
- Classified as a peptide and therapeutic peptide
- Related to metabolic disease research
- Acts as an AP-1 activator
Medchemexpress LLC LIH383 TFA | 2866266-58-0 | 99.8% | 997.22 | 5 MG
LIH383 TFA is a white to off-white solid that has been tested and complies with specifications, exhibiting a high purity of 99.83% by HPLC.
- Tested and complies with specifications
- High purity of 99.83% (HPLC)
- White to off-white solid appearance
- Store in sealed conditions away from moisture
- Powder stable for 2 years at -80°C or 1 year at -20°C
- In solvent, stable for 6 months at -80°C or 1 month at -20°C
Medchemexpress LLC MPSD TFA (MARCKS-ED TFA) | 99.8% | 3080.76 | 5 MG
MPSD TFA is the TFA salt form of MPSD, a 25-amino acid peptide derived from the effector domain sequence of the intracellular membrane protein myristoylated alanine-rich C-kinase substrate (MARCKS). It functions as a biological probe to study membrane curvature and lipid composition, specifically recognizing phosphatidylserine.
- TFA salt form of MPSD
- 25-amino acid peptide
- Derived from MARCKS protein
- Detects membrane curvature
- Identifies phosphatidylserine
- Useful as a biological probe
- White to off-white solid appearance
- Soluble in DMSO and H2O
Medchemexpress LLC Fti-276 trifluoroacetate | 1217471-51-6 | 98.0% | 547.6 g/mol | C23H28F3N3O5S2 | 10 MG
FTI-276 trifluoroacetate is the trifluoroacetate salt of a small-molecule inhibitor of protein farnesyl transferase. It is provided as a solid for research use and exhibits sub-nanomolar activity against both Plasmodium falciparum and human PFT, making it suitable for biochemical and antiparasitic research applications.
- Potent protein farnesyl transferase inhibition at sub-nanomolar concentrations.
- Provided as the trifluoroacetate (TFA) salt to aid handling and formulation.
- High reported purity, approximately 98%.
- Supplied in small, research-ready quantities suitable for assay development.
- Characterized by published chemical identifiers for unambiguous compound identification.
Medchemexpress LLC L-lysine, L-valyl-L-glutaminyl-L-isoleucyl-L-valyl-L-tyrosyl- (TFA) | 99.45% | 748.91 | 25 MG
PHF6 TFA is a self-assembly sequence capable of initiating the full-length tau protein aggregation, mapped to the third microtubule-binding repeat region of the tau protein. Aggregated PHF6 TFA potentiates NLRP3 inflammasome expression and autophagy in human microglial cells.
- Purity: 99.45%
- Molecular weight: 748.91 (free base)
- Chemical formula: C36H60N8O9.xC2HF3O2
- Appearance: Solid
- Color: White to off-white
- Sequence: Val-Gln-Ile-Val-Tyr-Lys
- Solubility in H2O: ≥ 50 mg/mL
- Store sealed and away from moisture
- Powder storage: -80°C for 2 years, -20°C for 1 year
- In-solvent storage: -80°C for 6 months, -20°C for 1 month
Medchemexpress LLC Homoglutathione trifluoroacetate | 435.37 | C13H20F3N3O8S | 25mg
Homoglutathione (TFA) is a biological molecule
Medchemexpress LLC FRETS-VWF73 TFA | 97.4% | 9340.61 | 5 MG
FRETS-VWF73 TFA is a 73-amino-acid peptide that functions as a fluorogenic substrate for ADAMTS13 assay.
- 73-amino-acid peptide
- Fluorogenic substrate for ADAMTS13 assay
- Excitation at 340 nm
- Emission at 450 nm
Medchemexpress LLC G7-18NATE TFA | 98.1% | 1417.50 | 1 MG
G7-18NATE TFA is a peptide inhibitor of Grb7. It binds to the Grb7-SH2 domain with micromolar affinity (Kd = 18.1 μM). G7-18NATE TFA inhibits cell proliferation, motility, cell invasion, and 3D culture formation in several cancer cell lines.
- Peptide inhibitor of Grb7
- Binds to the Grb7-SH2 domain with micromolar affinity (Kd = 18.1 μM)
- Inhibits cell proliferation, motility, cell invasion, and 3D culture formation in several cancer cell lines